核苷酸在婴儿奶粉里有啥作用 ?

核苷酸在婴儿奶粉里有啥作用 ?

我们都知道母乳是婴儿最好的食物。母乳中非蛋白氮约占总氮的25%,核苷酸总量占非蛋白氮的2%~5%[1]。核苷酸是核酸(nucleic acid)的基本组成单位,由碱基、五碳糖和磷酸构成。其中碱基是含氮的杂环化合物,包括嘌呤和嘧啶。五碳糖有核糖和脱氧核糖之分。碱基与五碳糖通过缩合反应形成核苷,核苷再与磷酸反应,脱水后形成磷脂键,生成核苷酸。除了构成核酸之外,在人体内,核苷酸还以其他衍生物的形式存在,参与各种物质代谢及功能调节活动,例如核苷酸是细胞内化学能的载体,如三磷酸腺苷(adenosine triphosphate,ATP)、三磷酸鸟苷(guanosine triphosphate,GTP),还能形成细胞信号转导过程中的第二信使(环腺苷酸、环鸟苷酸),以及形成各类辅酶等。

人体内的核苷酸主要由机体细胞合成,食物并不是主要来源,因此核苷酸的功效及机制研究不被重视。然而核苷酸对机体中生长代谢速度较快的免疫系统细胞、骨髓细胞、肠黏膜细胞等,以及机体在应激、创伤状态下非常重要[2-4]。研究还发现,对于早产儿、小于胎龄儿、坏死性小肠结肠炎患儿等,额外补充核苷酸,对于追赶生长以及疾病恢复有显著的帮助[5,6]。

临床研究发现婴儿配方奶粉添加核苷酸有多种优势,包括免疫、肠道健康、睡眠、代谢健康和体格生长。

重点来了,中国宝宝补充核苷酸要认准中国妈妈乳汁中的核苷酸比例,目前只有伊利金领冠研究并独家专利保护中国母乳的核苷酸比例,用于产品,大家一定要认准品牌和营养标签,支持我们的国货和有价值的中国发明专利。

参考文献:

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[3] J. R. Hess,N. A. Greenberg. The role of nucleotides in the immune and gastrointestinal systems: potential clinical applications[J]. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2012, 27(2): 281-94.10.1177/0884533611434933.

[4] J. D. Carver. Advances in nutritional modifications of infant formulas[J]. The American journal of clinical nutrition, 2003, 77(6): 1550s-1554s.10.1093/ajcn/77.6.1550S.

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